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Minimal (one)quinupristin/dalfopristin will increase the amount or outcome of paclitaxel protein sure by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.quinupristin/dalfopristin will lower the level or outcome of pyridoxine by altering intestinal flora. Applies only to oral sort of both equally brokers.